Centene shares surged 24.1% following a significant first quarter outperformance, driven by upside in both adjusted EPS and margin improvement across core Medicaid and Medicare businesses. Management raised full-year 2026 adjusted EPS guidance above the prior target, citing operational execution and favorable medical trends.

• Q1 adjusted diluted EPS came in at $3.37, above previous expectations and providing the basis to raise the full-year 2026 adjusted EPS outlook to greater than $3.40 (versus prior >$3).
• Medicaid operations outperformed on HBR, benefitting from lighter-than-forecast flu activity, weather-driven utilization tailwinds, and disciplined trend management actions.
• Medicare segment (Medicare Advantage and PDP) delivered better-than-expected HBR of 84.9% and reported gains from improved membership mix and higher retention.
• Commercial segment margins were in line with expectations; modest HBR pressure was offset by favorable SG&A.
• Management reiterated a prudent outlook for the remainder of the year but sees continued opportunity for margin advancement and operational improvement.