Sangamo Therapeutics reported significant advancements in its clinical pipeline for Fabry disease, highlighted by promising data from its STAAR study and a positive interaction with the FDA regarding its upcoming BLA submission.
- Presented compelling clinical data from the STAAR study, showing durable benefits of ST-920, with a mean annualized eGFR slope of nearly 2 at 52 weeks across all patients.
- FDA meeting confirmed agreement to use eGFR slope as an endpoint for an accelerated approval pathway, with plans for a BLA submission anticipated in early 2026.
- Initiated the Phase I/II STAND study for chronic neuropathic pain, expanding Sangamo's reach into neurology.
- Emphasized the strong safety profile and durable efficacy of ST-920, including encouraging cardiac data from treated patients.
- Focused commitment to addressing unmet needs within the Fabry community, bolstered by patient engagement and feedback.
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