Merck & Co., Inc. vs Pfizer Inc.

Full side-by-side comparison — 2026

Data as of Jun 11, 2026 · Updated automatically

MRK Wins

Tie

PFE Wins

MRK

Price USD 120.76

P/E Ratio 34.0x

Div Yield 0.0279%

Beta 0.22

Sector Health Care

PFE

Price USD 26.17

P/E Ratio 19.6x

Div Yield 0.0671%

Beta 0.30

Sector Health Care

Price Overview

Metric	MRK	PFE
Current Price	120.76	26.17
Previous Close	120.76	26.17

Valuation

Metric	MRK	PFE
Trailing P/E	34.03	19.61
Forward P/E	12.63	9.05
Price / Book	6.50	1.62
Price / Sales	4.54	2.31
EV / EBITDA	11.58	7.79

Dividends & Income

Metric	MRK	PFE
Dividend Yield	0.0279%	0.0671%
Dividend Rate (Annual)	3.32	1.72
5-Year Avg Yield	2.95%	4.48%
Payout Ratio	0.9212%	1.3054%

Risk & Financial Health

Metric	MRK	PFE
Beta (Volatility)	0.22	0.30
Debt / Equity	106.94	71.60
Quick Ratio	0.70	0.85
Current Ratio	1.30	1.25

Growth & Profitability

Metric	MRK	PFE
Revenue Growth	0.0490%	0.0540%
Earnings Growth	-0.1930%	-0.1010%
Return on Equity	0.1894%	0.0831%
Revenue / Share	26.42	11.13
Trailing EPS	3.55	1.31
Forward EPS	9.56	2.84

Analyst Targets

Metric	MRK	PFE
Analyst Mean Target	129.74	29.19
Analyst High Target	150.00	36.00
Analyst Low Target	100.00	24.00

Bottom Line: MRK vs PFE

Pfizer Inc. (PFE) leads on 11 of 19 comparable metrics.

Pfizer Inc. is the stronger pick for value investors, while Merck & Co., Inc. may appeal to other areas.

Pfizer Inc. has a lower Price / Book (1.62 vs 6.50), which may indicate the stock trades closer to its book value

Merck & Co., Inc. has a higher Forward EPS (9.56 vs 2.84), which suggests analysts expect higher future earnings per share

Merck & Co., Inc. has a higher Trailing EPS (3.55 vs 1.31), which means higher earnings per share over the last 12 months

This comparison is based on publicly available financial data and is for informational purposes only. It is not investment advice. Past performance does not guarantee future results.

PFE Pfizer Inc.

Best for Value Investors

• Lower Trailing P/E: 19.61

• Lower Forward P/E: 9.05

• Lower Price / Book: 1.62

Best for Income Investors

• Higher Dividend Yield: 6.71%

• Higher 5-Year Avg Yield: 4.48%

Analyst Upside / Downside

MRK

+7.4%

PFE

+11.5%

Based on analyst mean price targets. Estimates are not guaranteed and may not reflect future performance.

About These Companies

Merck & Co., Inc. (MRK)

Health Care · United States · NYQ

Merck & Co., Inc. operates as a healthcare company worldwide. It offers human health pharmaceutical for various areas under the Keytruda, Keytruda Qlex, Welireg, Gardasil, ProQuad, M-M-R II, Varivax, Vaxneuvance, Capvaxive, RotaTeq, Pneumovax 23, Bridion, Prevymis, Dificid, Zerbaxa, Winrevair, Adempas/ Verquvo, Ohtuvayre, Lagevrio, Isentress/Isentress HD, Delstrigo, Pifeltro, Belsomra, Januvia, and Janumet brands. The company also provides veterinary pharmaceuticals, vaccines and health management solutions and services, such as livestock products under the Nuflor, Bovilis/Vista, Bovilis Cryptium, Banamine, Estrumate, Matrix, Resflor, Zuprevo, …

View MRK details →

Pfizer Inc. (PFE)

Health Care · United States · NYQ

Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products in the United States and internationally. It operates in three segments: Biopharma, PC1, and Pfizer Ignite. The company offers internal medicine products, including cardiovascular metabolic diseases products under the Eliquis brand; migraine products under the Nurtec ODT/Vydura and Zavzpret brand; vaccines under the Prevnar family, Abrysvo, Nimenrix, FSME/IMMUN-TicoVac, and Trumenba brands; and Paxlovid for the treatment of COVID-19. It also provides inflammation and immunology products, such as Xeljanz, Enbrel, …

View PFE details →

Frequently Asked Questions

Which has a better dividend yield, MRK or PFE?

Pfizer Inc. currently has the higher dividend yield. Merck & Co., Inc. (MRK) yields 2.79% while Pfizer Inc. (PFE) yields 6.71%. Past dividends do not guarantee future payments.

Which is more volatile, MRK or PFE?

Pfizer Inc. is more volatile based on beta. Merck & Co., Inc. has a beta of 0.22 and Pfizer Inc. has a beta of 0.29. A beta above 1.0 means higher volatility than the overall market.

Which is cheaper by P/E ratio, MRK or PFE?

Pfizer Inc. has the lower trailing P/E ratio. Merck & Co., Inc. trades at 34.0x earnings while Pfizer Inc. trades at 19.6x. A lower P/E may suggest better relative value, but could also reflect lower growth expectations.

Which has more analyst upside, MRK or PFE?

Based on mean analyst price targets, Pfizer Inc. has more upside potential. Merck & Co., Inc. has +7.4% upside and Pfizer Inc. has +11.5% upside from current prices. Analyst estimates are not guaranteed.

Can I track both MRK and PFE in one portfolio?

Yes. AllInvestView lets you add both Merck & Co., Inc. and Pfizer Inc. to the same portfolio and monitor price changes, dividends, total return, and allocation — completely free.

Track MRK and PFE in Your Portfolio

Add both to AllInvestView and compare their real-time performance, dividends, and gain/loss side by side.

Start Free Portfolio